Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
6. Chromosomal Variation
Chromosomal Rearrangements: Translocations
1:54 minutes
Problem 13b
Textbook Question
Textbook QuestionAn animal heterozygous for a reciprocal balanced translocation has the following chromosomes:
MN • OPQRST
MN • OPQRjkl
cdef • ghijkl
cdef • ghiST
Identify the gametes produced by adjacent-2 segregation. Which if any of these gametes are viable?
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Reciprocal Balanced Translocation
A reciprocal balanced translocation occurs when two non-homologous chromosomes exchange segments without any loss of genetic material. This results in a rearrangement of genes but maintains the overall genetic balance. In heterozygous individuals, such as the one described, this can lead to unique patterns of gamete formation during meiosis, influencing genetic diversity and viability.
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Reciprocal Translocation
Adjacent-2 Segregation
Adjacent-2 segregation is a type of chromosomal segregation that occurs during meiosis in individuals with reciprocal translocations. In this process, homologous chromosomes segregate in such a way that two chromosomes from one pair and two from the other pair are pulled into the same gamete. This often results in gametes with an unbalanced set of chromosomes, which can lead to non-viable offspring due to genetic imbalances.
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Reciprocal Translocation
Viability of Gametes
The viability of gametes refers to their ability to develop into a functional organism upon fertilization. In the context of adjacent-2 segregation, gametes produced may carry duplications or deletions of genetic material, often rendering them non-viable. Understanding which gametes are viable requires analyzing the genetic content and ensuring that they possess the necessary chromosomal balance for successful development.
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Gamete Development
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