Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
19. Cancer Genetics
Overview of Cancer
1:59 minutes
Problem 2b
Textbook Question
Textbook QuestionA tumor is a growing mass of abnormal cells. Give an example from this chapter of a benign tumor that becomes a malignant tumor.
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Key Concepts
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Benign vs. Malignant Tumors
Benign tumors are non-cancerous growths that do not invade nearby tissues or spread to other parts of the body. They typically grow slowly and are often encapsulated, making them easier to remove surgically. In contrast, malignant tumors are cancerous, characterized by uncontrolled cell growth, invasion of surrounding tissues, and the potential to metastasize, or spread, to distant sites.
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Tumor Progression
Tumor progression refers to the process by which benign tumors can evolve into malignant tumors over time. This transformation often involves genetic mutations that enable the cells to acquire traits such as increased proliferation, resistance to cell death, and the ability to invade other tissues. Understanding this progression is crucial for cancer prevention and treatment strategies.
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Examples of Tumors
An example of a benign tumor that can become malignant is a colorectal adenoma, which is a polyp in the colon. While initially benign, certain adenomas can undergo dysplastic changes and develop into colorectal cancer if not monitored or removed. This highlights the importance of regular screenings and early intervention in preventing the progression of benign tumors to malignancy.
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