Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
20. Quantitative Genetics
Heritability
2:29 minutes
Problem 27b
Textbook Question
Textbook QuestionAnswer the following in regard to multifactorial traits in human twins. If the trait is produced with little contribution from genetic variation, what would you expect to see if you compared the concordance rates of MZ twins versus DZ twins? Explain your reasoning.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Concordance Rates
Concordance rates refer to the likelihood that both twins in a pair exhibit the same trait. In twin studies, these rates are compared between monozygotic (MZ) twins, who share nearly identical genetic material, and dizygotic (DZ) twins, who share about 50% of their genes. Higher concordance rates in MZ twins suggest a stronger genetic influence on the trait, while similar rates in both types of twins indicate a greater role for environmental factors.
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Multifactorial Traits
Multifactorial traits are characteristics influenced by multiple genetic and environmental factors. Unlike single-gene traits, these traits do not follow simple Mendelian inheritance patterns. Examples include height, intelligence, and susceptibility to diseases. Understanding that these traits arise from the interplay of various influences is crucial for interpreting twin studies and their findings.
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Genetic Variation
Genetic variation refers to the differences in DNA sequences among individuals, which can affect traits and predispositions to certain conditions. In the context of the question, if a trait shows little contribution from genetic variation, it implies that environmental factors play a more significant role. This would likely result in similar concordance rates for MZ and DZ twins, as the trait's expression is less dependent on genetic similarity.
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