Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
6. Chromosomal Variation
Chromosomal Rearrangements: Inversions
1:11 minutes
Problem 11
Textbook Question
Textbook QuestionContrast the genetic composition of gametes derived from tetrads of inversion heterozygotes where crossing over occurs within a paracentric versus a pericentric inversion.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Tetrads and Crossing Over
Tetrads are formed during meiosis when homologous chromosomes pair up. Crossing over occurs when segments of DNA are exchanged between these paired chromosomes, leading to genetic recombination. This process increases genetic diversity in gametes, which is crucial for evolution and adaptation.
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Crossing Over Terminology
Paracentric Inversion
Paracentric inversion is a chromosomal rearrangement where a segment of a chromosome is inverted but does not include the centromere. When crossing over occurs in paracentric inversion, it can lead to the formation of acentric fragments and dicentric chromosomes, which can result in gametes with missing or extra genetic material.
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Pericentric Inversion
Pericentric inversion involves the inversion of a chromosome segment that includes the centromere. During crossing over in pericentric inversions, the resulting gametes can have duplications and deletions of genetic material, affecting the viability of the gametes and the resulting offspring. This can lead to various genetic disorders or phenotypic variations.
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