Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
2. Mendel's Laws of Inheritance
Monohybrid Cross
3:16 minutes
Problem 10h
Textbook Question
Textbook QuestionThe dorsal pigment pattern of frogs can be either 'leopard' (white pigment between dark spots) or 'mottled' (pigment between spots appears mottled). The trait is controlled by an autosomal gene. Males and females are selected from pure-breeding populations, and a pair of reciprocal crosses is performed. The cross results are shown below.
Cross 1: P₁: Male leopard x male mottled
F₁: All mottled
F₂: 70 mottled, 22 leopard
Cross 2: P₁: Male mottled x female leopard
F₁: All mottled
F₂: 50 mottled, 18 leopard
Which of the phenotypes is dominant? Explain your answer.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Dominance in Genetics
Dominance refers to the relationship between alleles of a gene, where one allele masks the expression of another in a heterozygous condition. In this case, if all F₁ offspring from both crosses exhibit the mottled phenotype, it suggests that the allele for mottled is dominant over the allele for leopard.
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Variations on Dominance
Phenotypic Ratios
Phenotypic ratios are the relative frequencies of different phenotypes in the offspring of a genetic cross. The F₂ generation results show a consistent ratio of mottled to leopard phenotypes, which can be analyzed to determine the dominance of traits. The observed ratios (70 mottled: 22 leopard and 50 mottled: 18 leopard) support the conclusion that mottled is the dominant phenotype.
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Mutations and Phenotypes
Reciprocal Crosses
Reciprocal crosses involve switching the sexes of the parents in a genetic cross to determine if the inheritance pattern is influenced by sex. In this scenario, both crosses produced the same F₁ phenotype (all mottled), indicating that the trait's dominance is not sex-linked, reinforcing the conclusion that mottled is the dominant phenotype.
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Trihybrid Cross
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