In this chapter, we focused on a mode of inheritance referred to as quantitative genetics, as well as many of the statistical parameters utilized to study quantitative traits. Along the way, we found opportunities to consider the methods and reasoning by which geneticists acquired much of their understanding of quantitative genetics. From the explanations given in the chapter, what answers would you propose to the following fundamental questions:
How do we know that monozygotic twins are not identical genotypically as adults?
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
20. Quantitative Genetics
Heritability
Problem 16aKlug - 12th Edition
Textbook Question
In an assessment of learning in Drosophila, flies were trained to avoid certain olfactory cues. In one population, a mean of 8.5 trials was required. A subgroup of this parental population that was trained most quickly (mean=6.0) was interbred, and their progeny were examined. These flies demonstrated a mean training value of 7.5. Calculate realized heritability for olfactory learning in Drosophila.

1
Identify the formula for realized heritability: , where is the response to selection and is the selection differential.
Calculate the selection differential : .
Calculate the response to selection : .
Substitute the values of and into the heritability formula: .
Simplify the expression to find the realized heritability.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Heritability
Heritability is a measure of how much of the variation in a trait within a population can be attributed to genetic differences among individuals. It is expressed as a ratio ranging from 0 to 1, where 0 indicates that genetics do not influence the trait, and 1 indicates that genetics are solely responsible for the variation. Understanding heritability is crucial for predicting how traits may be passed on to future generations.
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Realized Heritability
Realized heritability refers to the proportion of phenotypic variance in a trait that is attributable to additive genetic variance, as observed in a specific population under certain environmental conditions. It is calculated using the formula: h² = R/S, where R is the response to selection (the difference in trait means before and after selection) and S is the selection differential (the difference between the mean of the selected parents and the overall population mean). This concept helps in understanding the effectiveness of selection in breeding programs.
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Olfactory Learning in Drosophila
Olfactory learning in Drosophila, or fruit flies, involves the ability of these insects to associate specific smells with positive or negative experiences, influencing their behavior. This learning process is often studied to understand the genetic and neural mechanisms underlying memory and learning. The training trials mentioned in the question reflect the number of attempts required for the flies to learn to avoid certain odors, which can be quantitatively analyzed to assess genetic influences on learning capabilities.
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