Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
2. Mendel's Laws of Inheritance
Monohybrid Cross
4:18 minutes
Problem 43
Textbook Question
Textbook QuestionA pure-breeding fruit fly with the recessive mutation cut wing, caused by the homozygous cc genotype, is crossed to a pure-breeding fly with normal wings, genotype CC. Their progeny all have normal wings. F₁ flies are crossed, and the F₂ progeny have a 3:1 ratio of normal wing to cut wing. One male F₂ fly with normal wings is selected at random and mated to an F₂ female with normal wings. Using all possible genotypes of the F₂ flies selected for this cross, list all possible crosses between the two flies involved in this mating, and determine the probability of each possible outcome.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Mendelian Genetics
Mendelian genetics is the study of how traits are inherited through generations based on the principles established by Gregor Mendel. It includes concepts such as dominant and recessive alleles, genotype, and phenotype. In this scenario, the dominant allele for normal wings (C) masks the recessive allele for cut wings (c), leading to the observed phenotypic ratios in the progeny.
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Descriptive Genetics
Punnett Square
A Punnett square is a diagram used to predict the genotypes and phenotypes of offspring from a genetic cross. It organizes the possible combinations of alleles from each parent, allowing for the calculation of probabilities for each genotype. In this case, constructing Punnett squares for the F₁ and F₂ generations will help determine the expected ratios of normal and cut wing flies.
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Chi Square Analysis
Probability in Genetics
Probability in genetics refers to the likelihood of certain genotypes or phenotypes occurring in offspring based on parental genotypes. It is calculated by considering all possible allele combinations and their frequencies. For the F₂ generation, the 3:1 ratio indicates that there is a 75% chance of producing a normal wing fly and a 25% chance of producing a cut wing fly when two F₂ flies are crossed.
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