In this chapter, we focused on extranuclear inheritance and how traits can be determined by genetic information contained in mitochondria and chloroplasts, and we discussed how expression of maternal genotypes can affect the phenotype of an organism. At the same time, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter, what answers would you propose to the following fundamental questions?
What key observations in crosses between dextrally and sinistrally coiled snails support the explanation that this phenotype is the result of maternal-effect inheritance?
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
3. Extensions to Mendelian Inheritance
Maternal Effect
Problem 2
Textbook Question
Write a short essay that distinguishes between organelle heredity and maternal effect.

1
Define organelle heredity: Explain that organelle heredity refers to the inheritance of genetic material found in organelles such as mitochondria and chloroplasts, which are passed down to offspring independently of nuclear DNA. Highlight that this type of inheritance is typically uniparental (often maternal) because organelles are usually inherited from the egg cell.
Define maternal effect: Describe the maternal effect as a phenomenon where the phenotype of an organism is determined by the genotype of its mother, rather than its own genotype. This occurs because the mother provides mRNA, proteins, or other factors in the egg cytoplasm that influence early development.
Contrast the genetic basis: Emphasize that organelle heredity involves the transmission of actual genetic material (DNA) located in organelles, while the maternal effect does not involve the inheritance of DNA but rather the influence of maternal gene products on the offspring's phenotype.
Discuss examples: Provide examples for each concept. For organelle heredity, mention mitochondrial diseases in humans or variegated leaf patterns in plants due to chloroplast inheritance. For maternal effect, mention the shell coiling direction in snails, which is determined by the mother's genotype.
Summarize the distinction: Conclude by summarizing that organelle heredity is about the inheritance of organelle DNA, while the maternal effect is about the influence of maternal gene products on the offspring's phenotype, with no direct inheritance of DNA involved.

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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Organelle Heredity
Organelle heredity refers to the transmission of genetic information through organelles, primarily mitochondria and chloroplasts, which contain their own DNA. This type of inheritance is maternal, as these organelles are typically passed from the mother to offspring through the cytoplasm of the egg cell. Consequently, traits associated with organelle DNA can exhibit unique patterns of inheritance that differ from Mendelian genetics.
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Maternal Effect
Maternal effect is a phenomenon where the phenotype of the offspring is determined not only by its own genotype but also by the genotype of the mother. This occurs because the mother provides specific substances, such as proteins and RNAs, to the egg that influence early development. As a result, even if the offspring has a different genotype, its initial traits can be significantly influenced by the maternal genotype.
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Differences in Inheritance Patterns
The key difference between organelle heredity and maternal effect lies in the source of genetic information. Organelle heredity involves the direct inheritance of organelle DNA, while maternal effect involves the influence of maternal contributions to the egg that affect the offspring's phenotype. Understanding these distinctions is crucial for studying inheritance patterns and the roles of maternal contributions in development.
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