Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
20. Quantitative Genetics
QTL Mapping
2:58 minutes
Problem 24b
Textbook Question
Textbook QuestionIn a series of crosses between two true-breeding strains of peaches, the F₁ generation was uniform, producing 30-g peaches. The F₂ fruit mass ranges from 38 to 22 g at intervals of 2 g. Using these data, determine the number of polygenic loci involved in the inheritance of peach mass.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Polygenic Inheritance
Polygenic inheritance refers to the genetic mechanism where multiple genes (loci) contribute to a single trait, resulting in a continuous range of phenotypes. In the case of peach mass, this means that several genes influence the weight of the fruit, leading to variations in the F₂ generation.
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Quantitative Trait Loci (QTL)
Quantitative Trait Loci are specific regions of the genome that correlate with variation in a quantitative trait, such as fruit mass. By analyzing the distribution of phenotypes in the F₂ generation, researchers can estimate the number of QTLs involved in the trait's inheritance.
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Phenotypic Variation and Distribution
Phenotypic variation refers to the observable differences in traits among individuals, which can be measured and analyzed. The range of peach masses from 22 g to 38 g indicates a continuous distribution, suggesting that multiple alleles contribute to the trait, which is a hallmark of polygenic inheritance.
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