Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
15. Genomes and Genomics
Comparative Genomics
2:03 minutes
Problem 17a
Textbook Question
Textbook QuestionYou have isolated a gene that is important for the production of milk and wish to study its regulation. You examine the genomes of human, mouse, dog, chicken, pufferfish, and yeast and note that all genomes except yeast have an orthologous gene.
What does the existence of orthologous genes in chicken and pufferfish tell you about the function of this gene?
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Orthologous Genes
Orthologous genes are genes in different species that evolved from a common ancestral gene and typically retain the same function. The presence of orthologs across diverse species suggests that the gene is conserved through evolution, indicating its importance in fundamental biological processes.
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Gene Conservation
Gene conservation refers to the preservation of gene sequences and functions across different species over evolutionary time. When a gene is found in multiple organisms, it implies that the gene plays a critical role in survival or reproduction, as it has been maintained despite the divergence of species.
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Functional Implications of Gene Presence
The presence of orthologous genes in species like chicken and pufferfish suggests that the gene in question likely has a similar function in these organisms. This functional conservation can provide insights into the gene's role in processes such as milk production, as it may be involved in essential biological pathways that are shared among these species.
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