Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
11. Translation
The Genetic Code
3:29 minutes
Problem 21a
Textbook Question
Textbook QuestionIn an experiment to decipher the genetic code, a poly-AC mRNA (ACACACAC...) is synthesized. What pattern of amino acids would appear if this sequence were to be translated by a mechanism that reads the genetic code as
a quadruplet with overlaps?
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Genetic Code
The genetic code is a set of rules that defines how the sequence of nucleotides in mRNA is translated into amino acids, the building blocks of proteins. It consists of codons, which are triplets of nucleotides, but in this case, we are considering a quadruplet reading frame. Each codon corresponds to a specific amino acid or a stop signal during protein synthesis.
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Quadruplet Codons
Quadruplet codons refer to a hypothetical reading frame where four nucleotides are read together as a single unit, rather than the standard triplet codons. This approach can lead to different amino acid sequences being produced from the same mRNA sequence, as the grouping of nucleotides changes the interpretation of the genetic code.
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Overlapping Reading Frames
Overlapping reading frames occur when the same nucleotide sequence can be read in multiple ways, allowing for different sets of codons to be formed from the same sequence. This can lead to the production of different proteins from a single mRNA strand, depending on how the reading frame is shifted or adjusted, which is particularly relevant when considering quadruplet codons.
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