Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
4. Genetic Mapping and Linkage
Crossing Over and Recombinants
5:42 minutes
Problem 27a
Textbook Question
Textbook QuestionIn tomatoes, the allele T for tall plant height is dominant to dwarf allele t, the P allele for smooth skin is dominant to the p allele for peach fuzz skin, and the allele R for round fruit is dominant to the recessive r allele for oblong fruit. The genes controlling these traits are linked on chromosome 1 in the tomato genome, and the genes are arranged in the order and with the recombination frequencies shown.
The F₁ are test-crossed to dwarf, peach fuzz, oblong plants, and 1000 test-cross progeny are produced. What are the phenotypes of test-cross progeny, and what number of progeny is expected in each class? <>
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Dominance and Alleles
In genetics, dominance refers to the relationship between alleles, where a dominant allele masks the effect of a recessive allele in a heterozygous individual. For example, in tomatoes, the allele T for tall plants is dominant over the recessive t for dwarf plants. This means that any plant with at least one T allele will exhibit the tall phenotype, while only plants with two recessive t alleles will be dwarf.
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Variations on Dominance
Linkage and Recombination
Linkage refers to the tendency of genes located close to each other on the same chromosome to be inherited together during meiosis. Recombination can occur during meiosis, leading to new combinations of alleles. The recombination frequency indicates how often crossing over occurs between linked genes, affecting the expected ratios of phenotypes in offspring, as seen in the test-cross progeny of the tomato plants.
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Chi Square and Linkage
Test Cross
A test cross is a breeding experiment used to determine the genotype of an individual with a dominant phenotype. This is done by crossing the individual with a homozygous recessive individual. In the context of the tomato question, the F₁ plants are test-crossed with dwarf, peach fuzz, oblong plants to reveal the phenotypes and expected ratios of the progeny, helping to infer the genetic makeup of the F₁ generation.
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