Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
4. Genetic Mapping and Linkage
Mapping Genes
1:23 minutes
Problem 33e
Textbook Question
Textbook QuestionHow would the results vary in cross (a) of Problem 32 if genes A and B were linked with no crossing over between them? How would the results of cross (a) vary if genes A and B were linked and 20 map units (mu) apart?
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Gene Linkage
Gene linkage refers to the tendency of genes located close to each other on the same chromosome to be inherited together during meiosis. When genes are linked, they do not assort independently, which can affect the ratios of offspring phenotypes in genetic crosses. Understanding linkage is crucial for predicting the outcomes of crosses involving multiple genes.
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Crossing Over
Crossing over is a process that occurs during meiosis where homologous chromosomes exchange segments of genetic material. This recombination can create new allele combinations, affecting the genetic variation in offspring. If genes A and B are linked with no crossing over, the parental combinations will be preserved, leading to fewer recombinant types in the offspring.
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Map Units and Genetic Distance
Map units, or centimorgans (cM), measure the distance between genes on a chromosome based on the frequency of recombination events. One map unit corresponds to a 1% chance of recombination occurring between two genes. If genes A and B are 20 map units apart, there is a 20% chance of recombination, which will increase the proportion of recombinant offspring compared to genes that are tightly linked.
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