Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
13. Gene Regulation in Eukaryotes
Epigenetics, Chromatin Modifications, and Regulation
3:36 minutes
Problem 23a
Textbook Question
Textbook QuestionMicrobiologists describe the processes of transcription and translation as 'coupled' in bacteria. This term indicates that a bacterial mRNA can be undergoing transcription at the same moment it is also undergoing translation. Is coupling of transcription and translation possible in single-celled eukaryotes such as yeast? Why or why not?
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Transcription
Transcription is the process by which the genetic information encoded in DNA is copied into messenger RNA (mRNA). In prokaryotes, this occurs in the cytoplasm, allowing for immediate access to ribosomes for translation. The enzyme RNA polymerase plays a crucial role in synthesizing the mRNA strand complementary to the DNA template.
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Eukaryotic Transcription
Translation
Translation is the process by which ribosomes synthesize proteins using the mRNA as a template. This occurs in the cytoplasm, where ribosomes read the mRNA sequence in codons and assemble the corresponding amino acids into a polypeptide chain. In bacteria, translation can begin even before transcription is complete, leading to the coupling of these processes.
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Translation initiation
Eukaryotic Cell Structure
Eukaryotic cells, such as those in yeast, have compartmentalized structures, including a nucleus where transcription occurs. This spatial separation means that mRNA must be processed and transported out of the nucleus before translation can begin in the cytoplasm. Consequently, the coupling of transcription and translation, as seen in bacteria, is not possible in single-celled eukaryotes due to this additional layer of complexity.
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Chromosome Structure