The apterous gene in Drosophila encodes a protein requir...

Question

The apterous gene in Drosophila encodes a protein required for wing patterning and growth. It is also known to function in nerve development, fertility, and viability. When human and mouse genes whose protein products closely resemble apterous were used to generate transgenic Drosophila [Rincon-Limas et al. (1999). Proc. Nat. Acad. Sci. (USA) 96:2165–2170], the apterous mutant phenotype was rescued. In addition, the whole-body expression patterns in the transgenic Drosophila were similar to normal apterous.

What do these results indicate about the molecular nature of development?

Accepted Answer

Hi, everyone. Welcome back. Let's look at our next question. It says which of the following genes established the anterior posterior pattern within each segment. So we look at our answer choices. We see we've got choice, a gap, jeans, choice B pair rule, genes, choice C segment, polarity genes and then choice d all of the above. So we do have the option for more than one correct answer. Well, hopefully we recall when we look at these three names of genes, those are the three categories of segmentation genes within the Drosophila embryo, and the segmentation genes of those genes that direct the development of dividing embryo into segments and then starting to establish the basic structure of the segments. So we're talking about which of those three will establish the anterior posterior pattern within the segment. So they're separate genes that established anterior posterior pattern um of the overall embryo. Those are those maternal effect genes, but within each segment, um we're looking for the genes that established the anterior posterior pattern. And we've actually got a nice clue if we don't recall that off the top of our head. When you look at choice E segment polarity genes right there in the name. And indeed choice c segment, polarity genes like and grilled, wingless and hedgehog are the genes that established this pattern. When we look at the other genes, um Choice a gap, jeans, gap, jeans are psychotic genes that divide the embryo into those basic body segments. That's sort of the beginning of segmentation. So they're not correct and therefore choice d all the above is not our answer. And then finally, choice B pair rule genes like hairy, even skipped. Um End up, there's I got genes that result in pairs of segments. So obviously, we've got pairs of legs, pairs of antenna established that pattern for the segments of the embryo. So that's why that's not correct. But again, which the following jeans established the anterior posture pattern within each segment. Choice C segment, polarity genes like in grail, wingless and hedgehog was a nice straight forward one for us. I hope to see in the next video.

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