For six genes known to be linked on chromosome 10 of corn (Zea mays), the recombination frequencies between various pairs have been determined in a series of genetic crosses. Use the recombination frequency data in the table below to determine the order of and distance between the genes on a genetic map. The gene lc1 is known to be closest to the telomere of the chromosome.

Verified step by step guidance

1. Identify the gene closest to the telomere, which is given as lc1.
2. List all the genes and their recombination frequencies with each other from the provided data.
3. Start with the gene lc1 and find the gene with the smallest recombination frequency to lc1, indicating it is the closest neighbor.
4. Continue adding genes to the map by selecting the next smallest recombination frequency with the last added gene, ensuring to check for consistency with previously mapped genes.
5. Calculate the genetic distances between each pair of adjacent genes on the map using the recombination frequencies, converting them into map units (centimorgans).

Key Concepts

Recombination Frequency

Recombination frequency is a measure of the likelihood that two genes located on the same chromosome will be separated during meiosis due to crossing over. It is expressed as a percentage, representing the proportion of recombinant offspring produced in a genetic cross. Higher recombination frequencies indicate that genes are further apart on the chromosome, while lower frequencies suggest they are closer together.

Genetic Mapping

Genetic mapping is the process of determining the relative positions of genes on a chromosome. This is achieved by analyzing recombination frequencies between pairs of genes, which allows researchers to create a linear representation of gene order and distances. Genetic maps are essential for understanding gene linkage and inheritance patterns in organisms.

Linkage and Gene Order

Linkage refers to the tendency of genes located close to each other on the same chromosome to be inherited together during meiosis. The order of linked genes can be determined by analyzing recombination frequencies; genes that are more likely to recombine are further apart, while those that are less likely to recombine are closer together. Understanding gene order is crucial for constructing accurate genetic maps.