Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
4. Genetic Mapping and Linkage
Mapping Genes
2:38 minutes
Problem 37
Textbook Question
Textbook QuestionFor six genes known to be linked on chromosome 10 of corn (Zea mays), the recombination frequencies between various pairs have been determined in a series of genetic crosses. Use the recombination frequency data in the table below to determine the order of and distance between the genes on a genetic map. The gene lc1 is known to be closest to the telomere of the chromosome.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Recombination Frequency
Recombination frequency is a measure of the likelihood that two genes located on the same chromosome will be separated during meiosis due to crossing over. It is expressed as a percentage, representing the proportion of recombinant offspring produced in a genetic cross. Higher recombination frequencies indicate that genes are further apart on the chromosome, while lower frequencies suggest they are closer together.
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Genetic Mapping
Genetic mapping is the process of determining the relative positions of genes on a chromosome. This is achieved by analyzing recombination frequencies between pairs of genes, which allows researchers to create a linear representation of gene order and distances. Genetic maps are essential for understanding gene linkage and inheritance patterns in organisms.
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Mapping Overview
Linkage and Gene Order
Linkage refers to the tendency of genes located close to each other on the same chromosome to be inherited together during meiosis. The order of linked genes can be determined by analyzing recombination frequencies; genes that are more likely to recombine are further apart, while those that are less likely to recombine are closer together. Understanding gene order is crucial for constructing accurate genetic maps.
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