Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
4. Genetic Mapping and Linkage
Mapping Overview
2:46 minutes
Problem 2b
Textbook Question
Textbook QuestionWrite a short essay that discusses how crossing over can be detected and how the resultant data provide the basis of chromosome mapping.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Crossing Over
Crossing over is a genetic process that occurs during meiosis, where homologous chromosomes exchange segments of genetic material. This exchange increases genetic diversity in gametes and can be detected through various methods, such as analyzing offspring phenotypes or using molecular markers. Understanding crossing over is essential for studying inheritance patterns and genetic variation.
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Genetic Mapping
Genetic mapping is the process of determining the location of genes on a chromosome and the distances between them. The data obtained from crossing over events can be used to create linkage maps, which illustrate the relative positions of genes based on the frequency of recombination. This mapping is crucial for identifying gene functions and understanding genetic disorders.
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Mapping Overview
Recombination Frequency
Recombination frequency is a measure of how often crossing over occurs between two genes during meiosis, expressed as a percentage. It is calculated by dividing the number of recombinant offspring by the total number of offspring. This frequency is directly related to the physical distance between genes on a chromosome, allowing researchers to estimate gene locations and construct genetic maps.
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