Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
3. Extensions to Mendelian Inheritance
Overview of interacting Genes
2:24 minutes
Problem 10b
Textbook Question
Textbook QuestionThree pairs of genes with two alleles each (A₁ and A₂, B₁ and B₂, and C₁ and C₂) control the height of a plant. The alleles of these genes have an additive relationship: Each copy of alleles A₁, B₁, and C₁ contributes 6 cm to plant height, and each copy of alleles A₂, B₂, and C₂ contributes 3 cm. Identify the number of different genotypes that are possible with these three genes.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Alleles and Genotypes
Alleles are different versions of a gene that can exist at a specific locus on a chromosome. In this scenario, each gene (A, B, C) has two alleles (A₁/A₂, B₁/B₂, C₁/C₂). A genotype is the combination of alleles an organism possesses for a particular gene, which can be homozygous (two identical alleles) or heterozygous (two different alleles). Understanding how these combinations form is crucial for determining the total number of genotypes.
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Additive Gene Interaction
Additive gene interaction occurs when the effects of different alleles contribute cumulatively to a phenotype, such as plant height in this case. Each allele contributes a specific amount to the trait, meaning that the total height can be calculated by summing the contributions from all alleles present. This concept is essential for understanding how multiple genes can influence a single trait and how to calculate the resulting phenotypic variations.
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Interacting Genes Overview
Combinatorial Genetics
Combinatorial genetics involves calculating the number of possible combinations of alleles from multiple genes. For each gene with two alleles, there are three possible genotypes (homozygous dominant, heterozygous, homozygous recessive). When considering multiple genes, the total number of genotypes is found by multiplying the number of genotypes for each gene, which is key to solving the question about the number of different genotypes possible with the three genes.
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