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Post-Translational Modification definitions Flashcards

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Post-Translational Modification definitions
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  • Post Translational Modification
    Chemical changes to proteins after synthesis, altering their function, location, or stability, and can include reversible modifications like phosphorylation, which can activate or deactivate proteins.
  • Protein
    A molecule composed of amino acids that undergoes post-translational modifications, such as phosphorylation, to regulate its function, location, activation, or degradation.
  • Phosphorylation
    Adding a phosphate group to a protein, which can reversibly activate or deactivate the protein, depending on the specific protein involved.
  • Phosphate Group
    A chemical group that, when added to a protein, can reversibly activate or deactivate the protein, functioning like a molecular switch.
  • Activation
    The process by which a protein's function is regulated through the reversible addition or removal of a phosphate group, altering its activity state.
  • Deactivation
    The process by which a protein's function is turned off through reversible post-translational modifications, such as the removal of a phosphate group.