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Introduction to Eukaryotic Gene Regulation exam Flashcards

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Introduction to Eukaryotic Gene Regulation exam
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  • Differential gene expression


    A process that allows multicellular organisms to express genes differently in different cells, leading to diverse cell types.

  • What is the role of histone acetylation in gene regulation?


    Histone acetylation modifies chromatin structure to make DNA more accessible for transcription.

  • Chromatin modifications


    Changes to the structure of chromatin that affect gene expression, including histone acetylation and DNA methylation.

  • What is the significance of DNA methylation?


    DNA methylation typically represses gene expression by adding methyl groups to DNA, affecting chromatin structure.

  • Transcriptional control


    Regulation of gene expression at the transcription stage, involving factors that influence the transcription of DNA to RNA.

  • What is the difference between euchromatin and heterochromatin?


    Euchromatin is less condensed and transcriptionally active, while heterochromatin is more condensed and transcriptionally inactive.

  • Post-translational modifications


    Chemical changes to proteins after they are synthesized, affecting their function and activity.

  • What is RNA interference?


    A process where RNA molecules inhibit gene expression by neutralizing targeted mRNA molecules.

  • Proteome


    The entire set of proteins expressed by a cell, tissue, or organism.

  • What is the function of general transcription factors?


    They are essential for the transcription of all genes and help position RNA polymerase at the start of transcription.

  • Post-transcriptional control


    Regulation of gene expression after transcription, including mRNA processing and degradation.

  • What is protein ubiquitination?


    A post-translational modification where ubiquitin proteins are attached to a substrate protein, often marking it for degradation.

  • Translational control


    Regulation of gene expression at the stage of translation, affecting how mRNA is translated into proteins.

  • What is the role of specific transcription factors?


    They regulate the transcription of specific genes by binding to DNA sequences near the genes they control.

  • Chromatin


    A complex of DNA and proteins that forms chromosomes within the nucleus of eukaryotic cells.

  • What is mRNA degradation?


    The process by which mRNA molecules are broken down, regulating the levels of mRNA available for translation.

  • Eukaryotic gene regulation


    The control of gene expression in eukaryotic cells, occurring at various stages such as chromatin modification, transcription, and translation.

  • What is the significance of differential gene expression in multicellular organisms?


    It allows for the development of diverse cell types despite having identical genomes.

  • Gene expression


    The process by which information from a gene is used to synthesize functional gene products like proteins.

  • What is the role of chromatin rearrangements in gene regulation?


    They alter the structure of chromatin to either promote or inhibit the transcription of genes.

  • What is the function of the nucleus in gene regulation?


    The nucleus is where chromatin modifications, transcription, and RNA processing occur.

  • What is the role of post-translational control?


    It involves modifications to proteins after synthesis, affecting their function and activity.

  • DNA methylation


    The addition of methyl groups to DNA, often serving to repress gene transcription.

  • What is the relationship between genome and proteome?


    The genome is the complete set of DNA, while the proteome is the complete set of proteins expressed by a cell.

  • Euchromatin


    A less condensed form of chromatin that is transcriptionally active.

  • What is the purpose of mRNA processing?


    To modify mRNA after transcription, including splicing, capping, and adding a poly-A tail, to protect and prepare it for translation.