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Classes of Signaling Receptors definitions Flashcards

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Classes of Signaling Receptors definitions
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  • Receptors Biomolecules


    Often proteins that change shape upon binding to specific ligands, initiating a cellular response. They can be located on the cell surface or within the cell.

  • Proteins


    Biomolecules that change conformation upon binding to specific ligands, facilitating various cellular processes, including signal transduction, metabolism, and structural support.

  • Conformation


    The three-dimensional shape or structure of a protein or molecule, which can change upon binding to a ligand or signaling molecule.

  • Ligand


    A molecule that binds specifically to a receptor, causing the receptor to change conformation and initiate a cellular response.

  • Signaling Molecule


    A chemical that binds to a specific receptor, triggering a cellular response, and can be hydrophilic or hydrophobic, affecting cells with corresponding surface or intracellular receptors.

  • Cell Surface Receptors


    Proteins embedded in the cell membrane that bind specific ligands, triggering a conformational change to initiate intracellular signaling pathways.

  • Intracellular Receptors


    Receptors located within the cell that bind to lipid-soluble signaling molecules, allowing them to directly influence gene expression by interacting with DNA in the nucleus.

  • Signal Transduction Pathways


    A series of molecular events where a cell converts an external signal into a functional response, often involving receptor activation, signal amplification, and cellular changes.

  • G Protein Coupled Receptors


    Cell surface receptors that activate intracellular G proteins upon ligand binding, initiating various signal transduction pathways.

  • GPCRs


    Transmembrane proteins that bind extracellular ligands, activating intracellular G proteins to trigger various cellular responses.

  • Receptor Tyrosine Kinases


    Cell surface receptors that, upon ligand binding, dimerize and autophosphorylate tyrosine residues, initiating intracellular signaling cascades.

  • RTKs


    Cell surface receptors that, upon ligand binding, dimerize and autophosphorylate tyrosine residues, initiating intracellular signaling cascades.

  • Domains


    Distinct functional and structural regions of a protein, often responsible for specific interactions or activities, such as binding ligands or catalyzing reactions.

  • Ligand Gated Ion Channels


    Membrane proteins that open to allow ion flow when a specific molecule binds, altering the channel's conformation.

  • Phosphorylation Cascade


    A series of protein phosphorylation events where each kinase activates another, amplifying the signal and leading to a cellular response.

  • Signal Transduction


    The process by which a cell converts an external signal into a functional change via receptor-ligand interactions, often involving a cascade of molecular events.