in-noncompetitive-inhibition-the-inhibitor-binds-to-the-allosteric-or-alternativ

Question

In noncompetitive inhibition, the inhibitor binds to the allosteric or alternative site on the enzyme. How does this process inhibit the substrate from binding in the active site?

Accepted Answer

By changing the conformation of the active site.

Answer

By directly blocking the substrate.

Answer

By dissolving the enzyme.

Answer

By deleting the active site.

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In noncompetitive inhibition, the inhibitor binds to the allosteric or alternative site on the enzyme. How does this process inhibit the substrate from binding in the active site?