Table of contents
- 1. Introduction to Biology2h 40m
- 2. Chemistry3h 40m
- 3. Water1h 26m
- 4. Biomolecules2h 23m
- 5. Cell Components2h 26m
- 6. The Membrane2h 31m
- 7. Energy and Metabolism2h 0m
- 8. Respiration2h 40m
- 9. Photosynthesis2h 49m
- 10. Cell Signaling59m
- 11. Cell Division2h 47m
- 12. Meiosis2h 0m
- 13. Mendelian Genetics4h 41m
- Introduction to Mendel's Experiments7m
- Genotype vs. Phenotype17m
- Punnett Squares13m
- Mendel's Experiments26m
- Mendel's Laws18m
- Monohybrid Crosses16m
- Test Crosses14m
- Dihybrid Crosses20m
- Punnett Square Probability26m
- Incomplete Dominance vs. Codominance20m
- Epistasis7m
- Non-Mendelian Genetics12m
- Pedigrees6m
- Autosomal Inheritance21m
- Sex-Linked Inheritance43m
- X-Inactivation9m
- 14. DNA Synthesis2h 27m
- 15. Gene Expression3h 20m
- 16. Regulation of Expression3h 31m
- Introduction to Regulation of Gene Expression13m
- Prokaryotic Gene Regulation via Operons27m
- The Lac Operon21m
- Glucose's Impact on Lac Operon25m
- The Trp Operon20m
- Review of the Lac Operon & Trp Operon11m
- Introduction to Eukaryotic Gene Regulation9m
- Eukaryotic Chromatin Modifications16m
- Eukaryotic Transcriptional Control22m
- Eukaryotic Post-Transcriptional Regulation28m
- Eukaryotic Post-Translational Regulation13m
- 17. Viruses37m
- 18. Biotechnology2h 58m
- 19. Genomics17m
- 20. Development1h 5m
- 21. Evolution3h 1m
- 22. Evolution of Populations3h 52m
- 23. Speciation1h 37m
- 24. History of Life on Earth2h 6m
- 25. Phylogeny2h 31m
- 26. Prokaryotes4h 59m
- 27. Protists1h 12m
- 28. Plants1h 22m
- 29. Fungi36m
- 30. Overview of Animals34m
- 31. Invertebrates1h 2m
- 32. Vertebrates50m
- 33. Plant Anatomy1h 3m
- 34. Vascular Plant Transport2m
- 35. Soil37m
- 36. Plant Reproduction47m
- 37. Plant Sensation and Response1h 9m
- 38. Animal Form and Function1h 19m
- 39. Digestive System10m
- 40. Circulatory System1h 57m
- 41. Immune System1h 12m
- 42. Osmoregulation and Excretion50m
- 43. Endocrine System4m
- 44. Animal Reproduction2m
- 45. Nervous System55m
- 46. Sensory Systems46m
- 47. Muscle Systems23m
- 48. Ecology3h 11m
- Introduction to Ecology20m
- Biogeography14m
- Earth's Climate Patterns50m
- Introduction to Terrestrial Biomes10m
- Terrestrial Biomes: Near Equator13m
- Terrestrial Biomes: Temperate Regions10m
- Terrestrial Biomes: Northern Regions15m
- Introduction to Aquatic Biomes27m
- Freshwater Aquatic Biomes14m
- Marine Aquatic Biomes13m
- 49. Animal Behavior28m
- 50. Population Ecology3h 41m
- Introduction to Population Ecology28m
- Population Sampling Methods23m
- Life History12m
- Population Demography17m
- Factors Limiting Population Growth14m
- Introduction to Population Growth Models22m
- Linear Population Growth6m
- Exponential Population Growth29m
- Logistic Population Growth32m
- r/K Selection10m
- The Human Population22m
- 51. Community Ecology2h 46m
- Introduction to Community Ecology2m
- Introduction to Community Interactions9m
- Community Interactions: Competition (-/-)38m
- Community Interactions: Exploitation (+/-)23m
- Community Interactions: Mutualism (+/+) & Commensalism (+/0)9m
- Community Structure35m
- Community Dynamics26m
- Geographic Impact on Communities21m
- 52. Ecosystems2h 36m
- 53. Conservation Biology24m
12. Meiosis
Genetic Variation During Meiosis
4:34 minutes
Problem 4a
Textbook Question
Textbook QuestionA planet is inhabited by creatures that reproduce with the same hereditary patterns seen in humans. Three phenotypic characters are height (T=tall, t=dwart), head appendages (A=antennae, a=no antennae), and nose morphology (S=upturned snout, s=downturned snout). Since the creatures are not 'intelligent,' Earth scientists are able to do some controlled breeding experiments using various heterozygotes in testcrosses. For tall heterozygotes with antennae, the offspring are tall antennae, 46; dwarf antennae, 7; dwarf no antennae, 42; tall no antennae, 5. For heterozygotes with antennae and an upturned snout, the offspring are antennae upturned snout, 47; antennae downturned snout, 2; no antennae downturned snout, 48; no antennae upturned snout, 3. Calculate the recombination frequencies for both experiments.
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Identify the parental and recombinant phenotypes for each experiment. In the first experiment, the parental phenotypes are tall with antennae and dwarf with no antennae. The recombinant phenotypes are dwarf with antennae and tall with no antennae. In the second experiment, the parental phenotypes are antennae with upturned snout and no antennae with downturned snout. The recombinant phenotypes are antennae with downturned snout and no antennae with upturned snout.
Calculate the total number of offspring for each experiment. For the first experiment, add 46 (tall antennae) + 7 (dwarf antennae) + 42 (dwarf no antennae) + 5 (tall no antennae) to get a total of 100 offspring. For the second experiment, add 47 (antennae upturned snout) + 2 (antennae downturned snout) + 48 (no antennae downturned snout) + 3 (no antennae upturned snout) to get a total of 100 offspring.
Calculate the number of recombinant offspring for each experiment. In the first experiment, add 7 (dwarf antennae) + 5 (tall no antennae) to get 12 recombinant offspring. In the second experiment, add 2 (antennae downturned snout) + 3 (no antennae upturned snout) to get 5 recombinant offspring.
Calculate the recombination frequency for each experiment by dividing the number of recombinant offspring by the total number of offspring and then multiplying by 100 to convert to a percentage. For the first experiment, (12 recombinant / 100 total) * 100 = 12%. For the second experiment, (5 recombinant / 100 total) * 100 = 5%.
Interpret the results. The recombination frequencies of 12% and 5% indicate the degree of linkage between the genes. Lower percentages suggest closer linkage between the genes involved.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Mendelian Genetics
Mendelian genetics is the study of how traits are inherited through generations based on the principles established by Gregor Mendel. It involves understanding dominant and recessive alleles, genotype versus phenotype, and the segregation and independent assortment of alleles during gamete formation. This framework is essential for analyzing inheritance patterns in the described breeding experiments.
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Mendelian and Population Genetics
Recombination Frequency
Recombination frequency is a measure of the likelihood that two genes will be separated during meiosis due to crossing over. It is calculated by dividing the number of recombinant offspring by the total number of offspring, providing insight into the genetic linkage between traits. Understanding this concept is crucial for interpreting the results of the breeding experiments and determining the genetic distance between the traits studied.
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Allele Frequencies
Testcross
A testcross is a breeding experiment used to determine the genotype of an individual exhibiting a dominant phenotype. By crossing the individual with a homozygous recessive partner, researchers can observe the phenotypes of the offspring to infer the unknown genotype. This method is particularly relevant in the context of the question, as it allows scientists to analyze the inheritance patterns of the creatures' traits.
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