Which of the following correctly describe an active site? Select True or False for each statement. T/F It is the location in an enzyme where substrates bind. T/F It is the place where a molecule or ion binds to an inactive enzyme to induce a shape change to make it active. T/F It is the portion of an enzyme where chaperones bind to help enzymes fold. T/F It is the site on an enzyme where catalysis occurs.

Verified step by step guidance

1. Step 1: The active site of an enzyme is the region where the substrate binds. So, the statement 'It is the location in an enzyme where substrates bind.' is True.
2. Step 2: The active site is not typically where a molecule or ion binds to induce a shape change in the enzyme. This usually occurs at a different site, known as the allosteric site. So, the statement 'It is the place where a molecule or ion binds to an inactive enzyme to induce a shape change to make it active.' is False.
3. Step 3: Chaperones are proteins that assist in the folding of other proteins, including enzymes. However, they do not typically bind at the active site of the enzyme. So, the statement 'It is the portion of an enzyme where chaperones bind to help enzymes fold.' is False.
4. Step 4: The active site is indeed where the enzyme catalyzes the reaction, converting the substrate into the product. So, the statement 'It is the site on an enzyme where catalysis occurs.' is True.
5. Step 5: In summary, the active site of an enzyme is the location where substrates bind and where catalysis occurs. It is not typically the site where allosteric regulators bind or where chaperones assist in protein folding.