What characteristic distinguishes true multicellularity from colonies of cells?

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1. Identify the basic structure of a colony of cells, which is a group of similar cells that are physically connected but each cell operates as an independent unit, performing all the functions necessary for its survival.
2. Understand the structure of a truly multicellular organism, where cells are specialized for specific functions and cannot survive independently outside the organism.
3. Recognize that in true multicellularity, cells are not only physically connected but also communicate extensively with each other, coordinating their functions for the benefit of the entire organism.
4. Consider the role of cellular differentiation in true multicellularity, where cells develop into different types based on the needs of the organism, such as nerve cells, muscle cells, or blood cells.
5. Examine how the loss of any specialized cell type in a truly multicellular organism can affect the overall health and functioning of the organism, highlighting the interdependence of cells in these organisms.