Which of the following actions correctly describe a role performed by at least one type of intercellular connection? Select True or False for each statement. T/F Allows communication between adjacent cells. T/F Forms a watertight barrier between the cells. T/F Uses components of the extracellular matrix to indirectly connect adjacent cells. T/F Associates with cytoskeletal components to resist pulling forces.

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1. True - Gap junctions allow communication between adjacent cells by permitting the passage of ions and small molecules, facilitating intercellular communication.
2. True - Tight junctions form a watertight barrier between cells, preventing the passage of molecules and ions through the space between cells.
3. False - Intercellular connections such as gap junctions, tight junctions, and desmosomes directly connect cells rather than using components of the extracellular matrix.
4. True - Desmosomes are specialized structures that connect to intermediate filaments of the cytoskeleton, providing mechanical strength to tissues by resisting pulling forces.

Key Concepts

Intercellular Connections

Intercellular connections are structures that facilitate communication and adhesion between adjacent cells. They include tight junctions, gap junctions, and desmosomes, each serving distinct functions such as forming barriers, allowing ion and molecule passage, and providing mechanical strength.

Tight Junctions

Tight junctions are specialized connections that create a watertight seal between adjacent cells, preventing the passage of substances through the intercellular space. They are crucial in epithelial tissues, where they maintain distinct apical and basolateral surfaces, thus regulating permeability.

Gap Junctions

Gap junctions are intercellular channels that allow direct communication between adjacent cells by permitting the passage of ions and small molecules. They play a vital role in coordinating cellular activities, such as in cardiac muscle cells, where they facilitate synchronized contractions.