If you haven't answered the questions yet, pause the video now as we're about to go through all of the answers without stopping. Serum glutamate pyruvate transaminase and serum glutamate oxaloacetate transaminase are serum transaminase enzymes that are easy to measure and greatly increase when there's damage to the liver, which is not one of the answer choices. Serum creatine kinase is a serum kinase enzyme that is easy to measure and greatly increases when there is damage to the heart. Urea synthesis in mammals takes place mainly in the liver. You might recall that some of the reactions occur inside the mitochondria of the liver cells, and other reactions of the urea cycle occur in the cytosol of the cells, and while all tissues including the muscles ship glutamine to the liver to process nitrogen through the urea cycle, the muscles additionally send alanine, which can actually provide the liver with pyruvate for gluconeogenesis. Now, tetrahydrofolate and its derivatives shuttle one-carbon units between different substrates. You might remember that there are a lot of one-carbon transfer cofactors including biotin and S-Adenosyl Methionine. So these are all one-carbon unit shuttles. So, our cofactors to the one-carbon unit shuttles. Most amino acid degradation pathways lead to the citric acid cycle intermediates.
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation
Practice: Amino Acid Oxidation 1