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Amino Acid Oxidation definitions Flashcards

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Amino Acid Oxidation definitions
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  • Urea Cycle

    A liver process converting two nitrogens into one urea molecule, utilizing ATP, to safely excrete nitrogen.
  • Glutamine

    An amino acid transported from tissues to the liver, converted to glutamate, releasing ammonium for the urea cycle.
  • Glutamate

    Formed from glutamine in the liver, it is converted to alpha-ketoglutarate, releasing ammonium for the urea cycle.
  • Alpha-ketoglutarate

    A product of glutamate dehydrogenation, involved in the release of ammonium for the urea cycle.
  • Glucose-Alanine Cycle

    A process where muscles send alanine to the liver, linking amino acid metabolism with gluconeogenesis.
  • Transaminases

    Enzymes facilitating amino group transfer, indicating tissue damage, especially in liver and heart.
  • Carbamoyl Phosphate

    A molecule formed in the mitochondria, initiating the urea cycle by combining with ornithine.
  • Ornithine

    A molecule entering mitochondria to combine with carbamoyl phosphate, forming citrulline in the urea cycle.
  • Citrulline

    A molecule formed in the urea cycle, exiting mitochondria to combine with aspartate, forming argininosuccinate.
  • Argininosuccinate

    A molecule in the urea cycle cleaved into fumarate and arginine, linking to the citric acid cycle.
  • Fumarate

    A byproduct of the urea cycle, entering the citric acid cycle to be converted into malate and oxaloacetate.
  • Aspartate

    Formed from glutamate and oxaloacetate, it combines with citrulline in the urea cycle.
  • N-Acetylglutamate

    A molecule stimulating carbamoyl phosphate synthetase, regulating the urea cycle.
  • Glutaminase

    An enzyme converting glutamine to glutamate, releasing ammonium for the urea cycle.
  • Glutamate Dehydrogenase

    An enzyme converting glutamate to alpha-ketoglutarate, releasing ammonium and reducing NAD+ or NADP+.