The binding of an allosteric inhibitor to an enzyme causes the rate of product formation by the enzyme to decrease. Which of the following best explains why this decrease occurs?
A
The allosteric inhibitor binds to the active site, preventing the substrate from binding.
B
The allosteric inhibitor causes free energy change of the reaction to increase.
C
The allosteric inhibitor lowers the temperature of the active site.
D
The allosteric inhibitor binds to the substrate and prevents it from binding at the active site.
E
The allosteric inhibitor causes a structural change in the enzyme that prevents the substrate from binding at the active site.