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Ch. 12 Nervous Tissue
Martini - Fundamentals of Anatomy & Physiology 11th Edition
Martini, Nath, Bartholomew11th EditionFundamentals of Anatomy & PhysiologyISBN: 9780136874089Not the one you use?Change textbook
Chapter 12, Problem 8

Receptors that bind acetylcholine at the postsynaptic membrane are:
(a) Chemically gated channels
(b) Voltage-gated channels
(c) Passive channels
(d) Mechanically gated channels

Verified step by step guidance
1
Understand that acetylcholine is a neurotransmitter that binds to specific receptors on the postsynaptic membrane to initiate a response.
Recall that receptors which respond directly to neurotransmitters by opening ion channels are known as chemically gated (or ligand-gated) channels.
Recognize that voltage-gated channels open in response to changes in membrane potential, not directly by neurotransmitter binding.
Note that passive channels are always open and not gated by any stimulus, so they do not specifically bind acetylcholine.
Mechanically gated channels open in response to physical deformation of the membrane, which is unrelated to acetylcholine binding.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Acetylcholine Receptors

Acetylcholine receptors are proteins located on the postsynaptic membrane that specifically bind the neurotransmitter acetylcholine. These receptors mediate synaptic transmission by triggering ion flow across the membrane, leading to changes in the postsynaptic cell's electrical state.
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Chemically Gated Channels

Chemically gated channels, also known as ligand-gated channels, open or close in response to the binding of a specific chemical messenger like a neurotransmitter. When acetylcholine binds to these receptors, the channel opens, allowing ions to pass and generating a postsynaptic potential.
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Voltage-Gated vs. Other Ion Channels

Voltage-gated channels open in response to changes in membrane potential, unlike chemically gated channels that respond to ligands. Passive channels allow ions to move down their concentration gradient without gating, and mechanically gated channels respond to physical deformation, making them distinct from acetylcholine receptors.
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Ions: Anions vs. Cations